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However, it is crucial for our patients to understand that BPC-157 is not approved by the FDA for human use, and its safety and efficacy have not been fully established in clinical trials

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In conclusion, UCH-L1, USP22, OTUD5, and USP14 are promising therapeutic targets in DKD, but more clinical studies are needed to confirm safety and efficacy

NOs activation of Nrf2 in endothelial cells required an increase in free zinc level intracellularly but how zinc activates Nrf2 is not clear [89]

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