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Martinez FJ, Calverley PMA, Goehring U-M, Brose M, Fabbri LM, Rabe KF

In cells, Fe 3+ is reduced again to Fe 2+ by ferric reductase, and Fe 2+ is released into the labile iron pool (LIP) [32]

Ferroptosis is reversible (43), which has made research on ferroptosis and its relation to the formation of urolithiasis to have a very promising future, thus bringing a new direction for the treatment of urolithiasis

This methodological rigor ensures that observed therapeutic benefits reflect genuine restoration of mitochondrial bioenergetics rather than compensatory or off-target physiological adaptations

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