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10 (2019): e1002931

doi: 10.1038/s41380-018-0322-z 46 WangYGuanXChenXCaiYMaYMaJet al

Moreover, renal failure can be accompanied by increased levels of serum creatinine, blood urea nitrogen, urinary protein, inflammatory cytokines, profibrotic factors, lipid peroxidation, and mitochondrial dysfunction in the adenine diet [20], 5/6Nx [22], and UUO models [23,24]

In most of the studies, coenzyme Q 10 supplementation improved exercise tolerance and reduced or delayed electrocardiographic changes associated with myocardial ischemia compared to placebo