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A similar bidirectional relationship is observed between mitochondrial dysfunction and lipid accumulation, whereby impaired mitochondria exhibit continuous electron leakage from complex I of the, ETC, resulting in the generation of ROS

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doi: 10.1016/j.biochi.2021.03.001 214 DelporteCVirreiraMCrutzenRLouchamiKSenerAMalaisseWJet al