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Conclusion: Our study reveals robust predictive capacities of explainable machine learning models when applied to risk stratification using real-world data

[20] Mild to moderate pain at the injection site is common, and some may have redness or swelling

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The risk factors for the development of cardiovascular diseases include: hypertension, disorders in the lipid metabolism (such as hypercholesterolemia, hypertriglyceridemia and low concentration of HDL (high-density lipoprotein)), diabetes, obesity, low physical activity, alcohol consumption, smoking, menopause and exposure to xenobiotics [70,71,72]