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Two serial enzymatic reactions convert tryptophan to kynurenine, and the first and rate-limiting step is catalyzed by three different enzymes: IDO-1 (indoleamine 2,3-dioxygenase-1), IDO-2 (indoleamine 2,3-dioxygenase-2) or TDO (tryptophan 2,3-dioxygenase)

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The registered clinical study CTRI/2025/07/090519 confirmed that skin pH was unchanged in all 30 participants after treatment, which is direct instrument measured evidence that the product does not behave like bleach