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Investors believe it's a $1-billion-to-$3-billion-a-year market, but hard figures are elusive, because most peptides are sold on the quasi-legal gray market

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The article discusses the pharmacokinetic challenges peptides face, such as low oral bioavailability due to poor membrane permeability and enzymatic degradation in the gastrointestinal tract

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Even when ingested in normal amounts, copper and iron may become toxic in certain individuals with genetic predispositions that lead to hepatic overload - iron overload in hemochromatosis [11-17] or copper overload in Wilson disease [18-27]