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As expected, a 12-week course of HFD feeding induced early-stage liver pathologies of NAFLD in mice including fatty liver and liver injury, which were manifested by increased hepatic TG levels (Fig

Journal of China Agricultural University2023,28(5):120-127

doi: 10.1111/imr.13186 31 KroemerGGalassiCZitvogelLGalluzziL

Deleting miR-23a in T cells causes significant inflammation and severe liver damage [139]

Furthermore, since this study utilized a specific formulation of POPS in temperature-sensitive hydrogels, further optimization across different formulations and concentrations is needed to enhance its clinical relevance