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FASEB J 29:38633875

Proc Natl Acad Sci U S A (2017) 114(38):102149

(Osaka, Japan) and ACROS Organics (Fair Lawn, NJ, USA), respectively

Based on results thus far, we postulated the following model: while K48-linked ubiquitylation by UBR5 is restricted by OTUD5, TRIP12 assembles K29-linked chains, which are resistant to OTUD5 DUB activity