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24 Nuclear factor-erythroid 2 p45-related factor-2 (Nrf2) activation, a mechanism for cellular defense, also increases antioxidant production, such as glutathione, in response to reactive oxygen species

Methods We conducted a thorough search for observational studies, including prospective cohort, nested case-control, case-cohort or retrospective cohort studies, randomized controlled trials (RCTs), and non-RCTs from MEDLINE and EMBASE up to November 2023