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Die unterschiedlichen Mechanismen, die dabei ineinandergreifen, sind inzwischen gut erforscht: Glutathion reguliert den oxidativen Zustand innerhalb der Zellen

Howsoever, the synthesis of 3-HK from Kyn by the flavoprotein kynurenine-3-monoxygenase (KMO) is another critical point in the Kyn pathway, determining the balance between the neurotoxic component 3-HK and the neuroprotective KYNA [216]