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Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis

Indeed, a recent study reported no obvious decline in mitophagy in mice across all brain tissues with age, but rather region-specific dynamics (Rappe et al, 2024)

While normal cells preserve membrane localization of EAATs, their mislocalization in malignant cells together with up-regulation of xCT lead to aberrant handling of glutamate that induces high levels of glutamate in the extracellular space, as seen in gliomas (192) and in breast cancer, where endocrine therapy-resistant cells promote autophagy and glutamate import via EAAT2 (60, 193)

Bacterial cells were grown in tryptone-yeast extract-gelatin-volatile fatty acids-serum (TYGVS) medium at 37 C in an anaerobic chamber in the presence of 90% nitrogen, 5% carbon dioxide, and 5% hydrogen (Ohta et al, 1986)

Inflammation-induced iron transport and metabolism by brain microglia