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A preliminary study evaluating diabetic peripheral neuropathy has demonstrated that targeted supplementation with these active B-vitamins (along with pyridoxal 5'-phosphate) can actually increase epidermal nerve fiber density, meaning the nerves physically begin to regrow and heal, leading to a reduction in pain and paresthesia

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Taking between 6 and 10 micrograms a day may help ensure youre getting enough B12

When you sleep with your foot in a neutral position, the fascia doesn't contract overnight, so there's nothing to pull apart when you stand up

Headache represents another occasionally reported effect, potentially related to the peptide's vasodilatory properties