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However, the powder must be reconstituted (dissolved back into liquid form) before it can be used in research applications

Use this design when: You have a smaller sample size available Individual differences are likely to be large The effects of the treatment are temporary You can effectively control for order and carryover effects 5

In addition, mitochondrial dysfunction in oligodendrocytes results in endoplasmic reticulum stress 8,9,10 , causing further downregulation of myelin proteins 11 and reduced myelin lipid synthesis 4