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Teofoli, P

To determine whether the TGF pathway might be affected by emphysema pathogenesis, we used seven previously published studies that had examined the effect of TGF ligands on gene expression to develop a collection of signatures of TGF pathway activation [1923, 30, 31]

Understanding tesofensine's unique mechanism and risk profile helps determine if this powerful but controversial weight loss compound merits consideration despite its FDA rejection and safety concerns

HGF/c-Met neurotrophic signaling Examined as a small-molecule tool for the hepatocyte growth factor/c-Met pathway, a target explored for neurodegeneration research