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Ashwagandha has historically been used to treat a variety of conditions, including weakness, erectile dysfunction, performance anxiety in males, and decreased desire for sex in both sexes [171, 196, 197]

Cyclooxygenase & Drugs Affecting the Prostanoid Pathway Cyclooxygenase (COX) is an enzyme that catalyzes the rate-determining step in the conversion of arachidonic acid to prostanoids by a 2-step process involving oxygen (Figure 2)