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In PD animal models, Bcl-2 family proteins exhibit abnormal expression following neuronal lesions, which triggers apoptotic cascades and contributes to further degeneration of brain regions (Table 1)

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However, caution should be taken in designating the effects of pleiotropic cytokines such as TGF-

Tryptophan, an essential amino acid, is metabolized by bacteria to produce indole and its derived metabolites, and in recent years, it has been regarded as an important signaling molecule that links the microbiota to host immunity 164

In vivo characterization of pulsatile GH release via GHS-R signaling