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To view a copy of this license, visit About this article Cite this article Woolston, C., Zhang, L., Storr, S

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A., Horner, J

The remaining carbon-centred radical, forms a resonance structure sharing this unpaired electron among carbons 9 to 13

Moreover, removing an H-atom from the sugar molecule at the C-4 location forms a free radical that initiates breakage in a single-stranded DNA [122]

In a DSS-induced mouse model of colitis, these inhibitors demonstrated significant therapeutic efficacy without noticeable toxicity, suggesting that dual inhibition strategies may offer new perspectives for IBD treatment [465]