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GLP-1 receptor agonists such as semaglutide reshaped obesity pharmacology by curbing appetite and improving glycemic control, but researchers hypothesized that recruiting the glucagon receptor could add a complementary axis increased energy expenditure and enhanced hepatic fat handling that a pure GLP-1 agonist cannot reach

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Systematic review of Crizanlizumab: a new parenteral option to reduce vaso-occlusive pain crises in patients with sickle cell disease

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