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1 Introduction Vitiligo is a skin depigmentation disease characterized by the loss of melanocyte function or reduction in melanocyte count

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Nonetheless, the aforementioned animal models, although extremely useful in investigating specific molecular mechanisms in the pathogenesis of ulcerative colitis, do not truly recapitulate disease as observed in patients, as IBD is a multifactorial disease and most clearly is not caused by a single mutation or defect in cellular or molecular pathways