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(April 2010)

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Dysregulation of ACE2 and Its Downstream Pathway Angiotensin converting enzyme 2 (ACE2) primarily catalyzes the breakdown of angiotensin II (AngII) to maintain the homeostasis of renin-angiotensin-aldosterone system (RAAS) as a pivotal counter-regulator, which is crucial for the physiology and pathology of most human organs (, )

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