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To further substantiate the pathway-level findings, a heatmap of representative immune-related differentially expressed genes was generated (Fig

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Chem Res Toxicol 22:708716

10.1073/pnas.97.13.7551 Proc

The search strategy combined keywords and Medical Subject Headings (MeSH) including subclinical hypothyroidism, zinc, selenium, micronutrients, thyroid hormones, deiodinase, selenoproteins, autoimmune thyroiditis, and trace elements. Priority was given to peer-reviewed experimental studies, randomized controlled trials, observational studies, systematic reviews, and meta-analyses investigating mechanistic pathways or clinical outcomes related to micronutrient status and thyroid function