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BOX 74-2 Conditions That May Benefit from Carnitine Supplementation Arrhythmias and cardiotoxicity induced by drugs Familial endocardial fibroelastosis Idiopathic mitral valve prolapse Elevated triglyceride levels Enhancing physical performance Fatigue in person with celiac disease Alzheimers disease, senile depression, and age-related memory defects Kidney disease and hemodialysis Alcohol-induced fatty liver disease Low sperm counts and decreased sperm motility Chronic obstructive pulmonary disease Acquired immunodeficiency syndrome Inborn errors of amino acid metabolism Carnitine is available in several different forms

4 , e179 (2015)

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Introduction Chronic pain and depression are leading causes of disability that are frequently encountered comorbidly in a variety of clinical conditions, sharing genetic and psychological risk factors, a relapsing-chronic course, and neurobiological features (Meyer et al., 2007