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Half of the tumor and lung tissue was chopped and digested (collagenase 2 mg/mL (Sigma-Aldrich)) for 45 min to 1 h at 37 C at 160 RPM

Renthal, W

Non-alcoholic fatty liver disease now affects roughly 25% of adults globally, driven by excess fructose consumption, insulin resistance, and visceral fat accumulation

*Correspondence: Marcia Hiriart, [email protected] This article was submitted to Diabetes: Molecular Mechanisms, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

They start as red spots that hurt when touched, but they eventually grow in size and rupture, leaking fluids