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Glucose metabolism in cancer cells

Mitoxantrone Theoretically, quercetin might increase the effects and adverse effects of mitoxantrone

We then tested whether other agents that specifically caused nucleotide imbalance (rather than the DNA-driven and RNA-driven effects of 5FU) have the same mechanism of action

Toyota M, Spencer D, Sawai-Toyota S, Jiaqi W, Zhang T, Koo AJ, Howe GA, Gilroy S (2018) Glutamate triggers long-distance, calcium-based plant defense signaling

This includes coordinated effects on both innate and adaptive responses and is mediated by engagement of key inflammatory and antioxidant signaling pathways (Figure 3)