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DOSING & ADMINISTRATION TB-500 is administered via subcutaneous injection

A vial stored at the wrong temperature, exposed to light, or reconstituted with the wrong water can lose a significant percentage of its activity before the first dose is drawn

At higher doses, it is also absorbed by passive diffusion across the gut wall, independently of intrinsic factor

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If the testing occurs as part of preventive screening, proper modifiers must be appended to comply with CMS 2025 guidelines