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Numerous clinical studies have demonstrated that IGF-1/IGF-1R mutations are associated with mental retardation and microcephaly [34, 35] (Table 2)

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The link between ER stress, ethanol metabolism, and apoptosis highlights the multifaceted nature of the cellular response to chronic alcohol exposure

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Domnguez-Avila JA, Salazar-Lpez NJ, Montiel-Herrera M, Martnez-Martnez A, Villegas-Ochoa MA, Gonzlez-Aguilar GA (2022) Phenolic compounds can induce systemic and central immunomodulation, which result in a neuroprotective effect