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Another study also elucidated that AARS1 can function as a lactate sensor, catalyzing the generation of lactate-AMP, and mediating the lactylation of p53, and the lactylation of p53 will inhibit its liquid-liquid phase separation, DNA binding capabilities, and ultimately lead to a decrease in transcriptional activity, fostering the onset and development of tumors

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MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention

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We used UCT-MSC-EXs to help combat MSC depletion and exosomes to improve intercellular communication

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