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Limited penetration of the brain and spinal cord

Vetrano DL Journal article: WATER RESEARCH

SmTGR H571A pH titration To understand the influence proton concentration has on the rate of formation of the broad charge transfer, which has previously been assigned to the proximity of the C159 thiolate and FAD isoalloxazine (Smith et al., 2023), pH titrations of the U597C and the H571A variants SmTGR reductive half-reactions were performed

The term complete biochemical response was defined as the normalization of serum transaminases and IgG levels below the upper limit of normal within 6 months of treatment initiation