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The results demonstrated no significant changes in body weight across all groups over the 15-day treatment period, suggesting that the therapeutic protocols did not induce noticeable systemic toxicity

[513] extensively review the involvement of BBB breakdown and dysfunction in neurological deficits and other pathologies, including chronic conditions (Alzheimer's disease, Parkinsons disease, amyotrophic lateral sclerosis, and multiple sclerosis), as well as acute CNS disorders such as stroke, traumatic brain injury, spinal cord injury, and epilepsy

it is expressed in almost all the mammalian cells, though at much lower levels

Glucose as a Risk Factor for Atherosclerosis