Clin Pharmacol Ther 2003
Pomegranate-derived compounds have been shown to modulate a wide range of molecular targets, including transcription factors, pro- and anti-apoptotic proteins, cell cycle regulators, protein kinases, cell adhesion molecules, pro-inflammatory mediators, and growth factors across multiple cancer types, such as skin, breast, prostate, colon, and lung cancers (366, 367)
Effect of oral L-carnitine administration on insulin sensitivity and lipid profile in type 2 diabetes mellitus patients
1 Introduction Maintaining and improving the health of dairy cows is an important issue for farmers, as it directly impacts the productivity and longevity of their livestock ( L-carnitine can be synthesized endogenously from the amino acids lysine and methionine ( The systemic administration of lipopolysaccharides (LPS), which are PAMPs of the membrane of gram-negative bacteria, can experimentally induce an acute phase reaction, resulting in a high energy demand for the immune system ( This study focuses on peripheral blood mononuclear cells (PBMC), a diverse population of immune cells primarily consisting of different lymphocytes and monocytes ( In the field of immunological research, PBMC are a valuable cell type in vivo as well as ex vivo , to examine cellular metabolism under different conditions ( The present study aimed to gain deeper insights into the metabolism of PBMC under the conditions of L-carnitine oversupply and increased energy demand
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