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Description

Once mixed, some compounds may require refrigeration and have shorter usable timeframes

Inhibition of glutaminolysis with the glutamine analogue 6-Diazo-5-oxo-L-norleucine (DON) reduces immune-induced and autoimmune Tfh cellular and humoral responses, selectively targeting pathogenic auto-reactive immune cells while preserving the ability of Tfh to generate protective responses against pathogens (55)

Exemplary methods are described below

Front Immunol 15:1457213 Tosur M, Onengut-Gumuscu S, Redondo MJ (2025) Type 1 Diabetes Genetic Risk Scores: History, Application and Future Directions