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Description

Broadly neutralizing antibodies for HIV-1: efficacies, challenges and opportunities

In the 3-NP-induced HD mouse disease model, the nuclei surrounded by obvious focal diffuse gliosis were observed around the striatum and hippocampal brain slices in the 3-NP group

The results of Lei et al

Similar conformational changes between two particle states are seen in other GSH-binding enteroviruses, and thus the use of GSH affinity columns for enterovirus purification will likely select for the D-antigenic states and could lead to loss/removal of material for less stable viruses and VLPs 37