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Description

To identify metabolic alterations specific to OC, we performed metabolomic analysis of OC and benign ovarian tumors

doi: 10.1016/j.molcel.2022.03.022.E 10 DixonSJOlzmannJA

The identification of 2-hydroxyglutarate as an aberrant metabolite produced by mutant IDH1 or IDH2 enzymes in glioma and acute myeloid leukemia established a new concept of oncometabolites (Ward et al., 2010)