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Advancements in the field of nanotechnology in medicine over the last two decades have made it possible to incorporate a variety of therapeutic, sensing, and targeting agents into nanoparticles [32,33,34,35,36,37]

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While early stages of atherosclerosis dont have many symptoms, as plaque builds up and starts to block the artery it can cause: Chest pain Fatigue Shortness of breath Muscle weakness in your leg (from lack of circulation) Pain in your leg, arm, or anywhere that has a blocked artery Heart attacks can happen at a younger age in lupus patients than in the general population