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In addition to their ability to load nucleic acid molecules, inorganic nanoparticles often possess unique functionalities, making them an attractive strategy for gene delivery [107,108,109,110]

Among these tissues, cartilage is the main component that absorbs mechanical stress, cushioning bones from impacting each other during various weight-bearing activities

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Three individuals with POLG mutations died while being on KD, however, their survival was not different compared to individuals with POLG mutations without KD

The results from a controlled double-blind trial of 30 patients revealed that the supplementation of a formulation containing selenium with vitamins A, C, and E (Se-ACE) did not have any remarkable curative effect compared to a placebo 108