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Description

Samad, M

NRF2 is a member of a family of basic leucine transcription factors that binds to A ntioxidant R esponse E lements (AREs) in the promoter region of genes involved in redox regulation, proteostasis, DNA repair, prevention of apoptosis, iron and heme metabolism, and phase I, II, and III drug/xenobiotic metabolism (Hayes and Dinkova-Kostova, 2014