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Interestingly, our data show that the microbial processing of glucose inhibits the expression of gst-4, as 2-DG treated bacteria did not confer this same effect

Conclusion and future perspectives Although many questions remain unanswered, it is becoming increasingly clear that oxidative stress-induced damage to the TM is related to glaucoma, which may inspire futher studies to find better and more stable antioxidants and better models with which to elucidate the mechanisms involved, and to determine whether in vitro findings can translate into in vivo observations

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Coelho Neto A, Azevedo RP, Santos MBP, Galdieri L de C, DAlmeida V, do AJLG, et al

Transplantation (2019) 103(10):210512