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For example, research is investigating the use of GSH precursors, such as N-acetylcysteine (NAC), to enhance intracellular GSH levels and counteract oxidative stress in neurodegenerative conditions (Arakawa and Ito, 2007)

10.1590/S0100-879X2006000500003 169

These actions mainly include (1) the activation of innate and adaptive immune cells through bacterial components [e.g., CpG-rich oligonucleotides, lipopolysaccharides (LPSs), lipoteichoic acids (LTAs)], (2) energy metabolism [e.g., the production of short-chain fatty acids (SCFAs)], (3) the synthesis of secondary BAs, (4) other byproducts derived from potentially harmful bacteria (e.g., TMAO) [7274]

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade