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Alterations of methionine metabolism as potential targets for the prevention and therapy of hepatocellular carcinoma

Med Oncol 40(9):248 Horie Y et al (2021) Molecular basis for the disruption of Keap1Nrf2 interaction via hinge & latch mechanism

In summary, targeted silencing of CBS substantially suppressed the proliferation of STAD cells, diminished GSH production, and provoked oxidative stress within the STAD cells