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To further explore the relationship between STEAP3 and ferroptosis, we treated STEAP3-knockdown cells with Fer-1

Intranasal BBB bypass is a validated human pharmacological route actively used for other biologics (e.g., intranasal oxytocin and insulin)

FRET-based microscopy assay to measure activity of membrane amino acid transporters with single-transporter resolution

The biological effect thus persists well beyond plasma presence

The claims files are linked to the Medicare personal summary files, which contain patient demographics and eligibility information and the Chronic Conditions supplemental files