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Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma

Lead binds to protein sulfhydryl groups, depletes GSH, and enhances lipid peroxidation, while thallium damages mitochondrial function and increases ROS generation [77]

Such alterations can potentially result in cell death or cancer, with the most common repair pathway in metazoans, non-homologous DNA end joining, being more mutagenic than homologous recombination-mediated repair [153]

These trials should incorporate standardized protocols and biomarker-driven patient stratification to enhance reproducibility and outcome precision (Mushtaq and Rohit, 2025)

Consequently, the supplementation of exogenous antioxidants is a pivotal strategy for enhancing the quality of cryopreserved semen and fertilization efficiency [26]