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The damage compounds

PAI-1, MMP-1, MMP-3, TIMP-1 and desmosine were measured in the supernatant alone where they were most abundant

The SELECT trial [35] highlighted that semaglutide administered sc at a dose of 2.4 mg OW was effective in significantly reducing MACE by 20% and slowing the progression of CKD among non-diabetic overweight or obese individuals with preexisting CV