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Nevertheless, despite demonstrating potent in vivo effects, neither study performed side-by-side dose-response benchmarking against clinical ACE inhibitors (e.g., lisinopril or captopril) under identical assay conditions

10.3389/fnagi.2022.998292 94 YarmohammadiF.Wallace HayesA.KarimiG

Treatment Protocol Research Limitations Moderate sample size (n=45)

This leads to peripheral and hepatic insulin resistance and compensatory intra-portal hyperinsulinemia, which results in increased hepatic GH sensitivity that aggravates the condition further ( Table 1

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