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10.1007/s00204-015-1622-6 37 GrayL

High-intensity ultrasound treatment for vincristine-induced neuropathic pain

The simultaneous restriction of glucose and glutamine, while elevating non-fermentable, anti-inflammatory ketone bodies, can help restore the pH balance of the microenvironment while, at the same time, providing a non-toxic therapeutic strategy for killing most of the neoplastic cells

Quality control of ADCs must also address the payloads potency: the manufacturing process should consistently achieve the correct dosage of toxin per antibody, and ensure batch-to-batch consistency

Thiamine Mononitrate (Vitamin B1): Helps convert carbohydrates into energy, supports nerve function, and manages complications like nerve damage and weakness