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7 , ra45 (2014)

67 In line with a role of ATII in endothelial dysfunction and hypertension, numerous studies have now demonstrated that the therapy with angiotensin-converting enzyme inhibitors and AT-1 receptor blockers is associated with an improvements in endothelial responsiveness 68, 69, 70, 71, 72 (the existence of negative reports also needs to be acknowledged)

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PDGF, VEGF, TGF-, FGF-2 and etc.), which favours recruitment of different types of stromal cells, including PSCs, endothelial cells and immune cells to create a pro-tumour microenvironment