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The latter event results in transactivation of genes coding for antioxidant and cytoprotective enzymes such as heme oxygenase (Hmox1), Nqo1, glutathione peroxidase (GPX2) and many others (reviewed in 73 , 74 ) (Figure 2A)

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[1] Cell Line:Senescent Leydig cells Concentration:25 mM Incubation Time:3 days Result:Reduced the viability of senescent as compared to normal TM3 Leydig cells

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Decades of research have revealed multiple proteins and chemicals that regulate normal blood vessel formation, many of which are hijacked by cancer cells to promote tumor angiogenesis