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I have mentioned earlier four types of potential self-sustained inflammatory loops , one formed by the T cell, B cell and monocyte triangle, a second one due to the fact that microglial cells can both produce and be activated by inflammatory cytokines, a third one due to excessive unbuffered ROS levels and damaged mitochondria, leading to less ATP and more ROS production, and a fourth one to bacterial translocation through a damaged gut mucosa, which may sustain mucosal inflammation and permeability

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Ethics statement The animal study was approved by the Institutional Animal Care and Use Committee at Cairo University, Cairo, Egypt (Vet CU13102024983)

Lipotropic compounds including vitamins, nutrients, and other natural or pharmacological agents may be administered as injections or in the form of oral supplements

In grass carp, Zhang et al