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Among them, GSK-3 and MARK have received significant attention as potential therapeutic targets for AD treatment using kinase inhibitory drugs

1.3.2 Ferroptosis inhibitor 1.3.2.1 Small-molecule inhibitors that reduce the ferroptosis Iron chelating agents, such as DFO and dexrazoxane (DXZ), can selectively target intracellular Fe 2+ and prevent ROS produced by Fenton reaction, thus achieving the effect of inhibiting ferroptosis (67, 68)

but definitive evidence is lacking

2013), which is probably induced by higher ROS accumulation in older leaves, this high and comparatively stable glutathione level seems to be crucial for mitochondria and cell functioning and viability under non-stress and stress conditions (Zechmann 2017, 2020)