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looked at some clinical trial studies (Phases II and III)

Abstract Background Abnormal lipid droplet (LD) dynamics in oral squamous cell carcinoma (OSCC) indicate lipid metabolism alterations that facilitate malignancy progression

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A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily